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EVI-1Ecotropic Virus Integration Site-1
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References in periodicals archive ?
Evi-1 raises AP-1 activity and stimulates c-fos promoter transactivation with dependence on the second zinc finger domain.
The Evi-1 proto-oncogene encodes a transcriptional repressor activity associated with transformation.
Evi-1 promotes para-aortic splanchnopleural hematopoiesis through up-regulation of GATA-2 and repression of TGF-b signaling.
The Evi-1 zinc finger myeloid transforming gene is normally expressed in the kidney and in developing oocytes.
EVI-1, EVI-2, EVI-3 and EVI-4 were used at 3, 10, 100 and 300 [micro]g/ml and EVI-5 at 3, 10 and 100 [micro]g/ml (EVI-5 at 300 [micro]g/ml was not soluble in the aqueous assay mixture).
[O.sub.2.sup.-] generated in the xanthine/xanthine oxidase system was significantly decreased by EVI-1, EVI-2, and EVI-4 (10-300 [micro]g/ml), whereas EVI-3 up to 300 [micro] g/ml and EVI-5 up to 100 [micro]g/ml had no effect (Fig.
EVI-1, EVI-2, EVI-3 and EVI-4 (10-300 [micro]g/ml), but not EVI-5 even at the highest concentration of 100 [micro]g/ml, suppressed O[H.sup.[dot]] produced in the Fenton-type reaction system in a concentration-dependent manner (Fig.