Furthermore, appropriate PEEP levels can also help stabilize the alveoli and avoid derecruitment by increasing the end-expiratory lung volume
. A previous study has indicated that LPV might be beneficial for the lungs; it may impair the cardiovascular system for the use of PEEP.
Due to the provision of distending pressure and increase in end-expiratory lung volume, some researchers proposed that it decreased airway resistance and flushed nasopharyngeal dead space, thereby contributing to the reduced work of breathing [17,18].
Fraser, "Oxygen delivery through high-flow nasal cannulae increase end-expiratory lung volume and reduce respiratory rate in post-cardiac surgical patients," British Journal of Anaesthesia, vol.
Rello, "Effect of high-flow nasal cannula and body position on end-expiratory lung volume: A Cohort Study Using Electrical Impedance Tomography," Respiratory Care, vol.
Sliwinski, "Reliability of inspiratory capacity for estimating end-expiratory lung volume changes during exercise in patients with chronic obstructive pulmonary disease," American Journal of Respiratory and Critical Care Medicine, vol.
Bye, "End-expiratory lung volume during arm and leg exercise in normal subjects and patients with cystic fibrosis," American Journal of Respiratory and Critical Care Medicine, vol.
The active use of the expiratory muscles (as during exercise) can produce auto-PEEP with normal or even subnormal end-expiratory lung volumes
. Gas trapping in dependent lung regions often occurs in the setting of ARDS, but this regional auto-PEEP is almost always relieved by modest levels of external PEEP that counter the compressive effects of the heavy lung on the dependent airways.
The slight pressure swings, minute volumes and unique flow characteristics of HFOV enhance lung recruitment and create higher end-expiratory lung volumes
. The stable MAP stabilizes the lung field and eliminates the potential for cyclical recruitment-derecruitment of the lung.