(CD105) as a urinary and serum marker of prostate cancer.
2 ALK-1, endoglin
(ENG) (with or without hereditary hemorrhagic telangiectasia 1.
Oxidative stress-induced S100B protein from placenta and amnion affects soluble endoglin
release from endothelial cells.
Placental productions and expressions of soluble endoglin
, soluble fms-like tyrosine kinasereceptor-1 and placental growth factor in normal and preeclamptic pregnancies.
Disturbed angiogenesis in systemic sclerosis: high levels of soluble endoglin
The monoclonal antibody SH-2, raised against human mesenchymal stem cells, recognizes an epitope on endoglin
a medical diagnostic company focused on acquiring, developing and commercializing diagnostic tests and risk assessment technologies for unmet clinical needs, announced today that Alere has exercised its exclusive option and licensed the novel biomarker Endoglin
from Miraculins, concluding a three-year Collaborative Research and Option Agreement program.
(CD105): a review of its role in angiogenesis and tumor diagnosis, progression and therapy.
A plethora of promising blood- and urine-based biomarkers have shown promise in early studies and are at various stages of development (Human kallikrein 2, Early Prostate Cancer Antigen, Transforming Growth Factor-Beta 1 and Interleukin-6, Endoglin
, PCA3, AMACR and ETS Gene Fusions).
2 ALK1, endoglin
(with or without hereditary haemorrhagic telangiectasia)
Mutations associated with HHT include: endoglin
mutation, activin receptor-like kinase (ALK)-1 mutation and SMAD4 mutation.
The two main genes that have been identified as contributing to HHT are the endoglin
(ENG) mutation on chromosome 9q33-34 and the activin-receptor-like kinase 1 (ACVRL1 or ALK1) on chromosome 12q (HHT Foundation International, 2010b).