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References in periodicals archive ?
[sup][27] Cerebral damage induced by oxidative stress during DHCA attracts lots of attention, and excitatory amino acids were observed to increase significantly after DHCA.
Rutherford, "Selective antinociceptive effect of excitatory amino acid antagonists in intact and acute spinal rats," Pharmacology, Biochemistry and Behavior, vol.
(9) reported that Mephenesin might be an antagonist of excitatory amino acids and might have NMDA-blocking activity and proposed that the NMDA-blocking activity of Mephenesin might be relevant to its muscle relaxing activity.
Grillner, "Excitatory amino acids and synaptic transmission: the evidence for a physiological function," Trends in Pharmacological Sciences, vol.
After traumatic brain injury the release of the excitatory amino acid glutamate (Glu) and aspartate (Asp), measured in interstitial fluid of the brain and in CSF, was strongly correlated with increased ICP, secondary brain injury, and poor outcome [32-34].
For example, in one study, the investigators injected a damage-triggering excitatory amino acid into rats and measured the amount of injury it created in a brain region called the hypothalamus.
Effects of ovarian steroids on gonadotropin response to N-methyl-D-aspartate and on hypothalamic excitatory amino acid levels during sexual maturation in female rats.
Ischemia of intact dorsal root ganglia (DRG) in situ leads to massive neuron death due to ischemia-triggered secondary events, such as massive release of excitatory amino acids from the neurons, their excessive accumulation and activation of neuron NMDA and other receptors, acidification, and loss of calcium homeostasis.
These findings suggest that increased plasma levels of the excitatory amino acid may be a risk factor for alcohol-induced brain atrophy, said Dr.
on a treatment for hyperparathyroidism (HPT); its calcilytics (for osteoporosis) program with with SmithKline Beecham PLC; its work on excitatory amino acid receptor antagonists with Eli Lilly and Co.; its partnership with Janssen Pharmaceutica Inc.
The excitatory amino acid receptors: their classes, pharmacology, and distinct properties in the function of the central nervous system.
Excitatory amino acids cause the death of neurons with toxicity, introduced via the aspartate receptor (aspartate is an excitatory amino acid).
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