EPSC

(redirected from Excitatory Postsynaptic Current)
AcronymDefinition
EPSCEuropean Planetary Science Congress (Russia)
EPSCEscola Politècnica Superior de Castelldefels (Spanish, University in Castelldefels, Catalonia)
EPSCExcitatory Postsynaptic Current
EPSCEarth and Planetary Sciences
EPSCEmployment Pass Services Centre (Singapore)
EPSCEuropean Process Safety Centre
EPSCErosion Prevention and Sediment Control
EPSCElectronic Product Stewardship Canada
EPSCElectronic Products and Systems Center
EPSCExcitatory Post Synaptic Current
EPSCEastern Pennsylvania Ski Council
EPSCElmbridge Phoenix Swimming Club (UK)
EPSCEconomic Policy and Summit Coordination (Department of State)
EPSCEmployer Productivity Superannuation Contribution
EPSCEngine Protection System Configuration
EPSCEnhanced Packet Switched Circuit
EPSCExecutive Program for Small Companies (Stanford University)
EPSCEstes Park Senior Center (Estes Park, Colorado, USA)
References in periodicals archive ?
The electrophysiological data obtained by recording in CA3 pyramidal neurons show some substantial differences in a number of features on both spontaneous excitatory postsynaptic currents (sEPSCs) and evoked excitatory postsynaptic currents (EPSCs) in mf-CA3 synapse in mice treated with H.
The propofol-induced changes in excitatory postsynaptic currents (EPSCs) and evoked EPSCs resulted from presynaptic GABA[sub]A receptor-mediated depolarization.[sup][11]
Spontaneous excitatory postsynaptic currents (sEPSCs) were recorded under voltage-clamp at -70 mV from CA1 pyramidal neurons after blocking the GABAA receptors by using 30 [micro]M bicuculline.
In a subsequent study, using whole cell recording from lumbar motoneurons, it was demonstrated that both AMPA and NMDA receptor-mediated excitatory postsynaptic currents were rapidly increased following bath application of TNF-[alpha] [115].
Abbreviations: NMJ: neuromuscular junction; CNS: central nervous system; mEPSCs: miniature excitatory postsynaptic currents; VGCC: voltage-gated calcium channel; p: release probability; GPCR: GTP-binding protein coupled receptors; PIP2: phosphatidylinositol-4,5-bisphosphate; AP: action potential.
Cochlear synaptic ribbon pairs consist of presynaptic ribbons, to which many synaptic vesicles are connected, and postsynaptic a-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs), which are glutamate receptors that mediate the excitatory postsynaptic currents of the SGNs' afferent dendrites [2].
However, in contrast to [Tsc1.sup.PC], in which PC postsynaptic currents were intact, in [Pten.sup.PC] mice, the excitatory postsynaptic currents (EPSCs) evoked by PF activity (PF-EPSCs) were aberrantly larger and those evoked by CF activity (CF-EPSCs) were smaller than in controls.
In hippocampal neurons of APP overexpressing transgenic mice, AMPAR-mediated excitatory postsynaptic currents are also significantly decreased [23].
In addition, rare spontaneous or miniature P2X-mediated excitatory postsynaptic currents were recorded at central synapses conveying the idea that ATP and postsynaptic P2X receptors do not act primarily as fast excitatory neurotransmitter at brain synapses [12] and, thus, despite the detection of several P2X subunits at the postsynaptic sites of glutamatergic synapses [15].
AMPA receptor-mediated miniature excitatory postsynaptic currents were isolated pharmacologically with 1 [micro]M tetrodotoxin (TTX), 20 [micro]M bicuculline, and 100 [micro]M DL-2-amino-5 phosphonopentanoic acid (DL-APV).
Incubation with TNF[alpha] increases the frequency of spontaneous excitatory postsynaptic currents (sEPSCs) in lamina II excitatory interneurons [60].
Spontaneous excitatory postsynaptic currents (sEPSCs) were counted and analyzed using the Mini-Analysis program (Synaptosoft, Inc., Decatur, GA, USA) as described previously [25].