F6P

AcronymDefinition
F6PFructose-6-Phosphate
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Previous studies in our lab have shown that F6P but not M6P under hypoxic conditions is capable of decreasing HIF-1[alpha] and CTGF, suggesting M6P has a mechanism of action unrelated to isomerization to F6P.
The effect of mannose-6-phosphate in reducing transforming growth factor proliferation of McCoy fibroblast cells
Thus, if the cell requires a significant amount of reducing power (NADPH), R5P will be converted back to F6P and GAP by transketolase generating NADPH.
Metabolic features of clear-cell renal cell carcinoma: mechanisms and clinical implications
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