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FABP 2 gene polymorphism and metabolic syndrome in elderly people of Croatian descent.
Synthesis of Antiproliferation sexual hormones Breast cancer EST p53, p21 Prostate cancer p53, p21, Kipl, IGFBP3, Per2, Clock, pAKT Ovary cancer p53, Apoptosis Cell cycle Antiangiogenesis Breast cancer p53, p21, p53, p21 Tie-2 caspase3, caspase7, caspase9, PARP, Bax, Bad, TGFb-1 Prostate cancer p53, p21, Kipl, p53, miRNA3195, JNK, p38, PKC, miRNA374b, HIF-1 caspase3, caspase8, caspase9, TGFb- 1, PARP, Bax Ovary cancer p53, caspase3, p53, Bax, PARP Invasion- metastasis Breast cancer E-cadherin, betal-integrin, ROCK, cadherinl3, GSK3[beta], Prostate cancer Ovary cancer FABP, ATP5F1B, HSP10 Table 3: Melatonin downregulated and/or inhibited molecular targets in breast, prostate, and ovary cancer.
Because Herbalog performance was favorable in ROC analysis, we applied the Herbalog tool to the identification of fatty acid-binding protein (FABP) 4 inhibitors from natural products.
(22.) Silva EP, Melo FABP, Sousa MM, Gouveia RA, Tenorio AA, Cabral AFF, et al.
Epidermal FABP (E-FABP) knockout mice were normal in gross and
FA transporters (FATP) and cytosolic FA-binding proteins (FABP) are probably involved in these processes (12).
Through its activities, ITC's Food and Agri-Business Programme (FABP) is developing scalable solutions by taking a market perspective.
"We have developed several mice models that are deficient in adipocyte/macrophage fatty acid binding proteins (FABP) and demonstrated that these animals were protected from some of the most detrimental effects of dietary intake of high levels of calories and fatty acids through alterations in the gene expression pattern of adipocytes, macrophages and systemic metabolic responses," he said.
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