FAMMMFamilial Atypical Multiple Mole Melanoma
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Kindreds with FAMMM have a 13- to 22-fold increased risk for pancreatic cancer (80) and the risk for pancreatic cancer among mutation carriers is 38-fold higher than that of the general population.
Although many reports have described the association of pancreatic carcinoma with FAMMM, no unique histopathologic features have been reported for the pancreatic cancers that develop in patients with FAMMM.
The association between FAMMM and pancreatic cancer suggests that a good family history of melanoma should be taken in patients with pancreatic cancer.