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Related to FANCC: FANCG
FANCCFanconi Anemia, Complementation Group C
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References in periodicals archive ?
There does not appear to be a significantly increased risk of cancer in carriers of mutations in the more common FA genes, including FANCA, FANCC and FANCG, [37] but larger studies are required to clarify this.
The initial study carried out in 2000 found that FANCA individuals with homozygous null mutations had a higher frequency of somatic anomalies than individuals with FANCC mutations, but a similar frequency to those with FANCG mutations.
Cells deficient in the murine Fanconi anaemia, complementation group C (Fancc) protein, one of the genes responsible for FA, are susceptible to [H.sub.2][O.sub.2] and cytokines.