Clinically the experimental group (n=51) treated with SSAET program, routine medication and dietary plan improved significantly in FBGL (pre-mean= 276.41+-25.31, post-mean=250.07+-28.23), PIL (pre-mean=13.66+-5.31, post-mean=8.91+-3.83), GC (pre-mean=8.31+-1.79, post-mean 7.28+-1.43), and IR (pre-mean=64.95+-27.26, post-mean 37.97+-15.58), as compared with patients in control group treated with routine medication and dietary plan in whom deteriorations were noted in FBGL (pre-mean = 268.19+-22.48, post-mean=281.41+-31.30), PIL (pre-mean=14.14+-5.48, post-mean=14.85+-5.27) GC (pre-mean=8.15+-1.74, post-mean=8.20+-1.44, and IR (pre-mean=64.49+-23.63, post-mean = 70.79+-23.30).
Statistically the experimental group showed significantly better improvements than control group in managing FBGL, plasma insulin level PIL, GC, and IR in T2DM.
Results of the current study showed that 51 patients with T2DM in experimental group who were treated three times a week for 25 weeks with SSAET program, routine medication and dietary plan produced significant improvements in FBGL, PIL, GC and IR as compared with the other 51 patients in control group treated for the same duration of time with routine medication and dietary plan.
They reported significant reduction in blood glucose level after exercise as compared with the baseline.10 Our results also showed marked reduction in FBGL among patients group treated with SSAET program, routine medication and dietary plan.
They reported both acute and chronic effects of exercise on insulin sensitivity, glucose homeostasis, and blood pressure and blood lipids, but the intensity, duration, and energy expenditure required to produce these effects are not clearly defined in the literature.11 The current study also showed improvements in FBGL, PIL, and glycemic control in experimental (exercise) group.
Several months of exercise significantly increase muscle response to glucose uptake without affecting glucose tolerance.17 Improvements in IR also resulted in our study by experimental group along with FBGL, PIL, and GC.