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14 gun boyunca kronik olanzapin (2 mg/kg; n=7) ve klozapin (2,5 mg/kg; n=7) uygulanmis ve davranis deneyine maruz kalmamis bir diger grup fare sakrifiye edildi ve hipokampal BDNF, CREB, NGF, sinapsin ve FGF2 gen ekspresyon seviyeleri degerlendirildi.
* Lipid Bilayer-based Carriers loaded with Polypeptide Growth Factors: sh-Oligopeptide-1 (EGF), -4(Thymosin-b4); sh-Polypeptide-1 (FGF2), -3(FGF7), -4(SCF), -5(TGFb3), -7(hGH), -9(VEGF), -10(FGF10), -11(FGFl), -15(TIMP2), -22(TGFbl), -28(PRL), -40(hPL), -59(PDGF), -71 (VIP), -78(HSP90A), -93(CTGF), -101 (Adiponectin)
The expression of GDF9, BMP15 and FGF2 have been reported in rodents, sheep's, buffalo and humans in oocyte, cumulus cells and ganulosa cells (4,5,8) and there is convincing evidence that they are important for ovarian function.
FGF2 and FGF10 are also expressed in adipose tissue and have each been implicated in adipogenesis.
In addition, we found marginal differences (p < 0.08) in the expression of NRG2, TGFA, and FGF2. Interestingly, the expression of all these nine factors was higher in both transplant groups (Tx1 and Tx2) than in both HC and DM controls (Supplemental Table 1).
Yu et al., "MiR-195 inhibits tumor growth and metastasis in papillary thyroid carcinoma cell lines by targeting CCND1 and FGF2," International Journal of Endocrinology, vol.
The cDNA was analyzed by real-time PCR using TaqMan Universal PCR Master Mix (Applied Biosystems) on an ABI 7500 Real-Time PCR System (Applied Biosystems) for the following molecules: rabbit ABCG2 (ATP-binding cassette sub-family G member 2), FGF2 (fibroblast growth factor 2), interleukin (IL)-1[beta], and IL-6.
Adipogenic impairment of adipose tissue-derived mesenchymal stem cells in subjects with metabolic syndrome: possible protective role of FGF2. J Clin Endocrinol Metab 2017;102:478-87.
In particular, PDAC cells stimulate PSC activation, proliferation, and migration through cytokines and growth factors such as pigment epithelium-derived factor (PEDF), platelet-derived growth factor (PDGF), PDGF-1, insulin-like growth factor (IGF), and ECM synthesis via TGF-[beta] and fibroblast growth factor 2 (FGF2) .
Sun et al., "Acute stress enhances adult rat hippocampal neurogenesis and activation of newborn neurons via secreted astrocytic FGF2," eLife, vol.
Negative control (CTRL-) consisted in FBS-free Endothelial Basal Medium-2 (EBM, Lonza); positive controls (CTRL+) consisted in Endothelial Growth Medium-2 (EGM-2, Lonza), supplemented with bullet-kit (VEGF, FGF1, FGF2, insulin, hydrocortisone, and heparin; Lonza) containing 10% of FBS.
En ratas, FGF2 y FGF9 actuan como morfogenos encargados de regular las interacciones epitelio-mesenquimaticas de celulas sustentaculares y peritubulares durante la formacion de los cordones testiculares y regulan selectivamente los patrones de expresion de proteinasas especificas e inhibidores, afectando ademas la remodelacion de la membrana basal (El Ramy et al.) (Fig.
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- FGF-inducible kinase