FGFIFree Grace Foundations International (Nigeria)
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In a recent study, Lea et al (2009) showed that FGFI, FGF3, FGF13, FGFI4, and FGF20 are expressed during embryonic eye development in Xenopus tropicalis.
laevis corneal explant cultures has shown that addition of FGFI protein, previously known as acidic FGF, or aFGF, to cornea explants induced the transdifferentiation of these cells into lens cells (Bosco et al., 1997b).
It is interesting to note that FGFI, FGFS, and FGF9, identified in our study as possible signaling candidates involved in lens regeneration, are members of three different FGF subfamilies (Itoh and Ornitz, 2004).