FIC1

AcronymDefinition
FIC1Familial Intrahepatic Cholestasis 1
References in periodicals archive ?
Interestingly, posttransplant development of inhibitory autoantibodies directed against FIC1 and MDR3 transporters with corresponding phenotypes has not yet been documented in patients with PFIC1 and PFIC3, respectively [44].
However, as well as the risks associated with these invasive procedures, other serious postoperative-related complications have been reported, particularly in PFIC1 patients with extradigestive symptoms, which can persist or even worsen, most likely due to extrahepatic expression of FIC1 [47].
Houwen, "FIC1 disease: A spectrum of intrahepatic cholestatic disorders," Seminars in Liver Disease, vol.
Baumann et al., "Sequencing of FIC1, BSEP and MDR3 in a large cohort of patients with cholestasis revealed a high number of different genetic variants," Journal of Hepatology, vol.
ATP8B1 encodes a P-type ATPase, FIC1, which is an aminophospholipid flippase that flips phosphatidylserine from the outer plasma leaflet of the canalicular membrane into the inner one.
Strain Median MIC ([micro]g/ml) (range) Compound COL EP1 LOB ATCC43300 (16-32) 32 (8-16) 8 32 AQ004 (32-64) 32 (8-16) 16 64 AQ006 (32-128) 128 (16-32) 16 (64-128) 64 AQ007 (64-128) 128 (16-32) 32 64 AQ012 (32-128) 64 (8-32) 16 (64-128) 64 Strain Median MIC ([micro]g/ml) (range) Compound PER PRO ATCC43300 (8-32) 32 (8-16) 16 AQ004 (32-64) 32 (4-16) 16 AQ006 (8-32) 16 (32-64) 32 AQ007 (4-32) 16 32 AQ012 (8-32) 16 (16-32) 32 Table 5 In vitro interaction between clindamycin and secondary metabolites from lichens as determined by non-parametric FIC1 and the [DELTA]E model (a).