FIGLAFactor in the Germline Alpha (gene)
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They are responsible for the follicle early growth and differentiation by control of a number of genes including NOBOX, FIGLA, BMP-15 and GDF-9(12).
Transcription factor FIGLA is mutated in patients with premature ovarian failure.
3 Steroidogenesis of the ovary NOBOX 7q25 Early folliculogenesis FIGLA 2q12 Zona pellucida gene regulation FOXL2 3q23 Granulosa cell differentiation and follicle development SOHL1/2 13q13.