FLIPIFollicular Lymphoma International Prognostic Index
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Among FL patients, 20 (68.9%) had a low or intermediate FLIPI risk score, and all patients had an ECOG score ≤2.{Table 1}
The numbers of cycles of completed treatment according to risk group (categorized by IPI or FLIPI score) of DLBCL and FL patients are listed in [Table 2].
The scoring systems, known as the IPI for DLBCL and FLIPI for FL, were used to compare results with clinical data.
Using these factors three groups are defined: low-risk; 0-1 factors; intermediate risk; 2 factors; and poor risk; greater than 3 factors, with 5-year overall survival (OS) rate from 52-91% and 10-year OS rate 36-73%.6 FLIPI risk categorisation is considered one of the best measures of outcome for FL along with tumour grade.8
This study was undertaken to determine the impact of FLIPI risk categorization on the survival of FL patients treated at our centre.
After collecting the data, FLIPI score and FLIPI risk categorisation was done i.e.
FLIPI risk categorisations according to FLIPI score from low to high risk were: low 21 (30%), intermediate 21 (30%) and high 28 (40%) respectively.
FLIPI: Follicular lymphoma international prognostic index.
OS at 5 years, according to FLIPI low risk, intermediate and high risk groups were 14 (66%), 10 (47%) and 7 (25%) respectively and the difference was statistically significant (p less than 0.02) (Figure-2).
FLIPI is a prognostic tool based on simple clinical parametres which are easy to use in clinical setting.
According to FLIPI risk categorisation, a study reported 5- year OS from 52-91 % for high-risk to low-risk groups.6 In our study, the 5-year OS for low, intermediate and high- risk groups according to FLIPI, were well predicted with statistical significance.