Since carnivore parvoviruses are likely to spread freely and rapidly in the environment when few cats and dogs are vaccinated against FPLV or CPV, CPV-2a/2b-type viruses seem to have more advantages over conventional FPLV in cats under natural conditions.
Note, however, that the experimental infection of SPF cats with FPLV generally leads to mild disease (23,24).
(38) compared the virulence between FPLV, CPV-2a, and CPV-2c in SPF cats.
Although isolation of FPLV from apparently healthy cats has been reported, feline parvoviruses are generally believed to be completely eliminated from recovered animals.
The Efficacy of Conventional FPLV Vaccines against CPV
The study of an attenuated live FPLV vaccine for CPV-2b infection has shown that vaccinated SPF cats are protected from challenge with CPV-2b at 2 weeks after vaccination (37).
Finally, we point out problems with the current nomenclature of carnivore paroviruses, including FPLV, MEV, and CPV.
The evolutionary pattern of FPLV in cats differs from that of CPV in dogs.