): The recorded results in Table 2 and Fig.
Initially, the student activists of the FQS
did sing 'Blowing in the Wind,' 'The Times They Are a-Changin'' and other songs by protest-era Dylan, but as attitudes hardened with government repression, these were soon replaced by 'Bangon' (The Internationale) and other Filipino revolutionary anthems at the barricades.
More recently, these warnings have been extended to include a potential risk for aortic dissection, with an increased risk from a baseline of 9/100 000 to 300/100 000, and a recommendation that the FQs
should be avoided in patients at risk of an aortic aneurysm, including the elderly and those with peripheral vascular disease, uncontrolled hypertension, vasculitic syndromes and diseases such as Marfan's and Ehlers-Danlos syndromes.
and rifaximin are also choices that can be used to treat severe, nondysenteric TD (both weak recommendations, moderate LOE).
enoxacin, fleroxacin, levofloxacin), others being employed in both human and veterinary medicine (Figure 1B-C) while some specific FQs
are only for veterinary use (Figure 2A-C) .
Ciprofloxacin (CFX), which is one of the second-generated groups of synthetic FQs
, can exhibit greater intrinsic antibacterial activity and make a broader antibacterial spectrum.
coli to various antibiotics with special reference to FQs
The liquid formulations of fluoroquinolones (FQs
) such as norfloxacin and nalidixic acid are manufactured by only two pharmaceutical companies (Table 1).
Multiple regression analysis indicated that the number of FQs
was related to TIRD and this was independently associated with the GDS.
employ their antibacterial effect by preventing bacterial DNA from unwinding and duplicating which takes place by inhibition of bacterial topoisomerase and gyrase.