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The Sombers research group has recently developed carbon nanotube yarns as microelectrodes for neurotransmitter detection using FSCV. They grew MWCNT arrays on quartz substrates via the "chloride mediated chemical vapor deposition (CVD) method" .
Wireless Instantaneous Neurotransmitter Concentration Systems (WINCS) were used for the data analysis software to integrate FSCV and digital telemetry.
It is impossible to directly compare each carbon electrode to the other due to differences in electrode size (diameter, shape, and morphology), method of electrode construction (i.e., glass, polyimide coated capillary insulations, etc.), and method of electrochemical detection (i.e., amperometry, differential pulse voltammetry, linear sweep voltammetry, fast scan cyclic voltammetry (FSCV), etc.).
Thus, electrophysiological, FSCV, and behavioral measurements demonstrate a role of dopamine signaling for pain and pain relief.
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