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A new class of miniaturized, robust, high speed, and cost-efficient FTIR systems can be addressed.
MEMS FTIR spectroscopy is one of the important applications of translational actuator-driven systems by using MEMS technology.
To the best of our knowledge, there is no literature data published on the solvent-free analytical method for the quantification of ciprofloxacin hydrochloride in bulk and tablet dosage form using FTIR. The objectives of present study were to develop and validate the FTIR method for quantification of ciprofloxacin in solid-state and evaluate the feasibility of DRIFTS application for pharmaceuticals.
The FTIR spectrum for pure sample of ciprofloxacin hydrochloride exhibited absorbance bands in the range of 3532,3373,3088,2932,2682,2620,1702,1623,1492,1446,1383, 1342, and 1267 [cm.sup.-1].
The FTIR spectra for the representative samples of tablet dosage forms diluted with potassium bromide are shown in Figure 4.
Traditionally, FTIR spectroscopy is employed for the qualitative analysis of pharmaceuticals; however, with advent in sampling techniques, DRIFT spectroscopy may serve as useful technique for qualitative and quantitative analysis of solid-state pharmaceuticals.
However, current methods for characterizing polymer composition gradients with traditional FTIR spectroscopy  are slow and inefficient.
Thin film composition gradients of poly(L-lactic acid) (PLLA) and poly(D,L-lactic acid) (PDLLA) blends were prepared on low emission reflective slides and were characterized with reflectance FTIR microspectroscopy.
2.2 FTIR Microspectroscopy: Construction of the Calibration Curve
The FTIR-RTM measurements were performed with a Nicolet Magna-IR 550 FTIR spectrophotometer interfaced with a Nic-Plan IR microscope.
On Perkin-Elmer's Spectrum RX, a new FTIR spectrometer, the instrument is visually divided vertically into thirds with the middle component colored a soft, pastel blue to the off-white of the outer thirds.
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