Antibody Distribution in The Two Groups Antibody Type Pregnant Group Other Patients (n=33) Group (n=62) Anti D 27 (81.8%) 11 (17.7%) Anti C 1 (3.0%) 3 (4.8%) Anti E 2 (6.1%) 6 (9.7%) Anti K 1 (3.0%) 3 (4.8%) Anti Le (a) 2 (6.1%) 9 (14.5%) Anti M 7 (11.3%) Anti
FyB 1 (1.6%) Anti D+M 1 (1.6%) Anti K+E 1 (1.6%) Anti Jk (a) 1 (1.6%) Anti S 1 (1.6%) Autoantibodies 15 (24.2%) Indeterminate 2 (3.2%)
"The limiting factor is how fast we can dump
FYBs on our first sorting table," Keever said.
These genes are Akt1, C3ar1, Ccl19, Ccr1, Cd97, Cxcl1,
Fyb, Ifi202b, Ifi203, Ifi204, Ifi205, Ikbke, Lyz1, Map3k13, Mapk10, Mapk10, Mapk13, Pln, Ppt1, Socs1, and Xiap.
Lo cual podria encontrar explicacion en el hecho de que
Fyb es el alelo ancestral y que la expresion de Fya resulta en una disminucion en la eficiencia de la union de P.
If the results from the screening procedure were positive, an extended panel of 12 cells with the following antigens was used to identify the antibody: C, c, D, E, e, Lewis (Lea, Leb), Kell (K), Kidd (JKa, JKb), Duffy (Fya,
Fyb), M, N, S, s, P1, and Lutheran (Lua, Lub).
Direct Antiglobulin Test Antiglobulin Test 1 Y K1 2 Y Positive for autoantibody 3 N Lea 4 Y History of DAT positivity Fya and autoantibody (autoantibody) 5 Y Positive for passive Negative anti-D 6 Y History of DAT positivity Negative (autoantibody) 7 N Positive for passive Passive anti-D and anti-D cold antibody 8 N Lea 9 Y Lea 10 N C 11 N D, E 12 N Positive for autoantibody Anti-E, DHTR vs DSTR discovered 13 N D 14 N K1 15 N Cold antibody, roleaux 16 Y History of DAT positivity Negative (autoantibody) 17 Y History of DAT positivity Negative (passive anti-D and autoantibody) 18 Y Positive for autoantibody E, C,
Fyb, and autoantibody 19 N K1, S 20 Y Leb 21 Y Positive for passive D anti-D 22 Y D 23 N D due to passive anti-D Hemolytic Blood Case Potential?