Aims: To study the clinical interest of fetal nasal bone length in predicting adverse pregnancy outcomes in the first trimester of pregnancy.
Results: Fetal nasal bone length >95th percentile was significantly associated with preterm labor and preterm premature rupture of membranes (p=0.02, accuracy 0.91 and p=0.001, accuracy 0.94, respectively), whereas nasal bone length >99th percentile was significantly associated with preterm labor and oligohydramnios (p=0.006, accuracy 0.95 and p=0.014, accuracy 0.97).
Conclusion: Fetal nasal bone length at high percentiles in the first trimester of pregnancy may aid in the prediction of adverse outcomes such as preterm labour, preterm premature rupture of membranes and oligohydramnios.
First-trimester fetal nasal bone length in an ethnic Chinese population.
They measured fetal nasal bone length and crown-rump length and recorded maternal characteristics, including self-reported ethnic origin, age, weight, and diabetes.
The weight of study participants ranged from 29.5 to 134 kg, but there was practically no difference in fetal nasal bone length by quartile of maternal weight.