(redirected from Free Concentration)
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References in periodicals archive ?
Increasing the value of the thermocapillary number [M.sub.1] or solutal capillary number [M.sub.2] can cause a descent in the free temperature [theta](1) and free concentration [phi](1) but a rise in the film thickness [beta], the skin friction coefficient -f" (0), the heat flux -[theta]'(0), and the free velocity f'(1).
For the study sample, we calculated conjugated concentrations as the difference between total and free concentrations, when both total and free concentrations were detectable.
The free concentration of HSA was 3.98 x [10.sup.-6] M when warfarin was added according to the equations of Table 1.
In many clinical situations, measurement of the total drug concentration does not provide the needed information concerning the free concentration of drug in plasma that is available for pharmacodynamic action; the present technique addresses this necessity.
This study was designed to evaluate the factors that influence the free concentration of the uremic retention solute p-cresol and also considers p-cresol and the clinical condition of the patients.
When the samples were divided into quartiles on the basis of total FREE concentration, the fourth quartile had values >10 000 ng/g in both studies.
The large amounts of data that were produced by the determination of these eight FREE concentrations for all segments of all samples cannot be fully included in this report.
(15) reported a correlation of the free concentrations of indoxyl sulfate and indole acetate and FFAs during HD with heparin anticoagulation.
Binding proteins likely also serve as a depot for hormones, allowing for longer half-life of the total hormone in circulation and continuous equilibration of the free concentration by dissociation from the bound depot.
The free concentration of L-dopa, which was analyzed by HPLC after ultrafiltration, was lower than the total L-dopa concentration in plasma.
However, the presence of increased concentrations of MPAG in such patients is an important contributor to increases in the pharmacologically active free fraction and free concentration of MPA because MPAG competes for MPA-binding sites on human serum albumin; therefore, MPAG may indirectly contribute to immunosuppression (3,13).
Although protein binding (99.8%), is about the same as for the younger group, the free concentration was significantly higher.