G6PD


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Related to G6PD: G6PD deficiency
AcronymDefinition
G6PDGlucose-6-Phosphate Deficiency
G6PDGlucosio 6-Fosfato Deidrogenasi (Italian)
G6PDGlucosamine-6-Phosphate Deaminase
G6PDGlucose-6-Phosphate Dehydrogenase (medical)
References in periodicals archive ?
Phenazopyridine should be used with caution especially for an infant younger than 1 month or with G6PD deficiency because of the risk for methemoglobinemia, sulfhemoglobinemia, and hemolytic anemia.
In active G6PD deficiency, Heinz bodies can be seen in red blood cells on a blood film, liver enzymes (to exclude other causes of jaundice) and Lactate dehydrogenase (elevated in hemolysis and a marker of hemolytic severity).
They also studied the propensity of these animals to develop cancer and found no difference, suggesting that enhancing G6PD activity does not have an important effect on the development of cancer.
11) While methylene blue is a recognized treatment for methemoglobinemia, it has oxidative effects, which may worsen the clinical situation especially in individuals with G6PD inducing acute hemolysis, thus further decreasing oxygen delivery to the tissues.
G6PD deficiency was detected in 71 anaemic children (24.
Patients present with jaundice in the neonatal period in hereditary spherocytosis, alpha thalassemia and G6PD and PK deficiency, whereas the first findings generally appear after the 4-[6.
This was oxidized to 6-phosphogluconate by G6PD with concomitant reduction of NADP.
Acute hemolytic crisis is the most common presentation of G6PD deficiency but in neonatal period it usually presents as jaundice.
A qualitative G6PD test was conducted and the patient was not found G6PD deficient.
G6PD activity was assayed by monitoring the NADPH production at 340 nm and the enzyme activity was expressed as [micro]mol [NADP.
Methemoglobinemia may also arise in patients with congenital G6PD deficiency, but this occurs infrequently because the enzyme plays a minor role in maintaining the reduction state of hemoglobin compared to b5-Met-Hb reductase (2).
Inherited blood disorders, such as sickle cell disease, the G6PD deficiency and Thalassaemia, are among the most challenging public health issues for the Omani authorities, particularly for the Ministry of Health.