GABHSGroup A Beta-Hemolytic Streptococci
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Cross-reaction between antibodies against streptococcal antigens produced following GABHS infections and basal ganglia antigens in children with genetic susceptibility is the main pathogenetic mechanism (2).
Paediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal Infection (PANDAS) is the acute onset of neuropsychiatric symptoms following GABHS infection.
Immune-mediated central nervous system manifestations of GABHS infection include SC, PANDAS, and a variety of neurobehavioral disorders.
Perianal streptococcal dermatitis (PSD) typically affects children 6 months to 10 years old and is usually caused by group A BHS (GABHS) with the species name Streptococcus pyogenes (2, 3).
As the signs and symptoms of GABHS pharyngitis overlap extensively with other infectious causes it is difficult to make a diagnosis based solely on clinical findings.
Clinical and epidemiological findings and diagnosis of pharyngitis due to group A f3-haemolytic streptococci (GABHS)
According to them, their study supports the hypothesis that some neuropsychiatric syndromes may be triggered by direct action of antibodies assocaiated with Strep throat bacteria, scientifically known as Group A beta-hemolytic streptoccoccus (GABHS), on the brain.