Thus GAHS has higher sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy when compared to mDF.
The GAHS is easy to calculate, involves markers for renal involvement and inflammation and is much more accurate than mDF.
The severity predicted by GAHS had an accuracy of 94% compared to that calculated by mDF, which had 72% accuracy.
These studies show the accuracy of GAHS in comparison with other prognostic scoring systems.
1) The GAHS score (94%) accurately predicted 1 month mortality when compared with mDF (72%).
2) The specificity and positive predictive value of GAHS (94.
Of these three patients, two had GAHS [greater than or equal to] 9 indicating that had GAHS been used to identify the severity.
4) One patient who died had both GAHS <9 and mDF <32.
It shows that baseline total bilirubin, creatinine, urea, MELD score and GAHS were significantly different among the patients who succumbed to the disease as compared to those who survived.
Patients with severe alcoholic hepatitis (Maddrey's discriminant function, [greater than or equal to] 32; or MELD score, [greater than or equal to] 21: or GAHS, [greater than or equal to] 9) who do not have sepsis should be given a trial of prednisolone at a dose of 40 mg per day for 28 days.
Higher bilirubin, creatinine, urea, MELD score and GAHS were found to be associated with the occurrence of increased mortality among patients with severe alcoholic hepatitis.