CP on day 16 , and Group III (GCEE + CP) received 100 mg/kgb.wt.
Since GCEE has been proven to be effective in vivo at doses of 10 mg/kg  and 150 mg/kgb.wt.
To study the effect of GCEE on the mRNA expression levels of caspase-3, BAX, inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), NF-[kappa]B, and PPAR[gamma] in the liver of CP-induced rats, quantitative RT-PCR was used as we previously reported .
Pretreatment of the CP-induced rats with GCEE produced significant (P < 0.001) reduction in serum aminotransferases and ALP activities.
Liver sections from GCEE pretreated rats showed noticeable amelioration of the liver histological architecture as depicted in Figure 2(d).
GCEE Mitigates CP-Induced Hematological Alterations in Rats.
Pretreatment of the CP-induced rats with GCEE significantly prevented leukopenia (P < 0.05) and thrombocytopenia (P < 0.05) as depicted in Figures 3(c) and 3(d), respectively.
GCEE Attenuates CP-Induced Oxidative Stress in the Liver of Rats.
GCEE administration prior to CP produced a significant (P < 0.05) improvement in liver GSH content.
GCEE Reduces CP-Induced Inflammation in the Liver of Rats.
To further confirm the anti-inflammatory effect of GCEE, the expression of COX-2, iNOS, and NF-[kappa]B was assayed in the liver of CP-induced rats.
(9.) We exclude "Teaching AP Economics" workshops from our variable indicating GCEE
workshop attendance because GCEE
is the official trainer of AP Economics teachers in Georgia--all AP Economics teachers have had this or a similar AP workshop.