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Crystal structure of GD2 bound pltb 5 SPLTB(A) 126.9 ACT.
Sample name [[chi].sub.ini] [[chi].sub.act] [Gd.sup.3+] [Gd.sup.3+] (mol.%) (mol.%) MNP-Gd0% 0 0 MNP- Gd0.5% 1 0.5 MNP- Gd0.6% 2.7 0.6 MNP- 5.6 2.5 Gd2.5% MNP- Gd5.1% 7 5.1 MNP- Gd4.3% 9 4.3 Sample name Lattice system [a.sp.(XRD)] ([Angstrom]) MNP-Gd0% Cubic ([section]) 8.368(8) MNP- Gd0.5% Cubic ([section]) 8.385(2) MNP- Gd0.6% Cubic ([section]) 8.348(3) MNP- Cubic 8.366(5) Gd2.5% + orth.
Gubala et al., "Inhibition of neuroblastoma tumor growth by targeted delivery of microRNA34a using anti-disialoganglioside GD2 coated nanoparticles," PLoS One, vol.
 investigated a descriptor named Grid D2 (GD2).
The cell surface receptors for BKPyV are disialic acid gangliosides GD1b, GT1b, GD3, and GD2 .
Other DSRCT targeted agents include GD2  and ganitumab, a fully human monoclonal antibody against type-1 insulin-like growth factor receptor (IGF-1R), showing 6% ORR and 17 (49%) SD rate in an open label phase II trial .
8 at GD2 (or GD3)--current electrode and GD3 (GD2), respectively--potential.
Its lead project, APN311 (ch14.18/CHO), is a chimeric monoclonal antibody against the GD2 antigen expressed on neuroblastoma and other tumors.
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