The ovine GDF9
gene map in chromosome five (Sadighi et al.
However, the BMP6, BMP15 and GDF9
mRNAs were most abundant in the oocyte, and their expression remained relatively constant during follicular development, whereas the BMPR1B and TGFBR1 were temporally regulated in different stages in pigs (Paradis et al., 2009).
BMP15 and GDF9
play a critical role in follicle development, oocyte maturation, ovulation and embryo development (8,9).
Study of mutations available in first-halfexon 2 of GDF9
gene in crossbred sheep born from crossing of Romanov rams with Kermani ewes.
Growth differentiation factor-9 (GDF9
) is a family member of transforming growth factor-[beta] (TGF[beta]) and is expressed by oocytes at a primary follicle stage and controls of gene expression in granulosa cells.
Expression of growth differentiation factor 9 (GDF9
), and bone morphogenetic protein 15 (BMP-15), and BMP receptors in the ovaries of goats.
Expression of Growth Differentiation Factor 9 (GDF9
), Bone Morphogenetic Protein 15 (BMP15), and BMP Receptors in the Ovaries of Goats.
"We believe that ASF 1A and GDF9
are two players among many others that remain to be discovered which are part of the cellular-reprogramming process," Cibelli said.
The art and artifact of GDF9
activity: Cumulus expansion and the cumulus expansion-enabling factor.