GHSR

AcronymDefinition
GHSRGrowth Hormone Secretagogue Receptor
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In the functional pathway of neuroactive ligand-receptor interaction, 5 genes NMUR2, GHSR, NMBR, GNRHR, and F2RL3 were involved.
Cardioprotection Effects of Sevoflurane by Regulating the Pathway of Neuroactive Ligand-Receptor Interaction in Patients Undergoing Coronary Artery Bypass Graft Surgery
As an endogenous ligand of GHSR, ghrelin was first isolated from the stomach of rats [4-6], and GHSR mRNA was expressed in the whole gastrointestinal tract and hypothalamus.
Atractylodin Induces Myosin Light Chain Phosphorylation and Promotes Gastric Emptying through Ghrelin Receptor
The report provides comprehensive information on the Growth Hormone Secretagogue Receptor Type 1 (GHS-R or GH-Releasing Peptide Receptor or GHRP or Ghrelin Receptor or GHSR), targeted therapeutics, complete with analysis by indications, stage of development, mechanism of action (MoA), route of administration (RoA) and molecule type.
New Report: Growth Hormone Secretagogue Receptor Type 1 - Pipeline Review, H1 2016
We investigated if ghrelin exerts its inhibitory effects on HO-8910 cells through GHSR activation and the downstream activity of MAPKs.
Ghrelin attenuates the growth of HO-8910 ovarian cancer cells through the ERK pathway
Ghrelin is the endogenous ligand of the growth hormone secretagogue receptor (GHSR) and is the first hormone linking gastrointestinal-pituitary axis.
Role of ghrelin in regulation of growth hormone secretion by Ghrelin-pituitary-GH axis linkage
Thus, the abovementioned genes, e.g., IGFBP 1-3, ODC, CCKAR, GHSR, and IGF1R, are not objects of our interest, since they are not located on chromosome 1.
Association between Motilin receptor gene haplotypes and growth traits in Japanese Hinai-dori crossbred chickens
In GC cells (a somatotrope tumor cell line) treated by GHRP-6 it has been observed that GHS increases GH release activating a G-protein coupled to the GHS receptor (GHSR), which activates the [IP.sub.3]-PKC signaling pathway [8].
Upregulation of voltage-gated calcium channel [Ca.sup.V] 1.3 in bovine somatotropes treated with Ghrelin
Because GHSR is expressed in lymphocytes, the action of ghrelin directly to preserve lymphocytes cannot be ruled out.
Ghrelin therapy improves survival after whole-body ionizing irradiation or combined with burn or wound: amelioration of leukocytopenia, thrombocytopenia, splenomegaly, and bone marrow injury
The effects of ghrelin are mediated via specific receptors, named the GH secretagogue receptors (GHSR) [30].
Severely obese adolescents and adults exhibit a different association of circulating levels of adipokines and leukocyte expression of the related receptors with insulin resistance
Ghrelin is secreted by X/A-like cells found in the gastric mucosa, and it binds to the growth hormone secretagogue receptor (GHSR) present at the end of the vagus nerve to stimulate feeding behavior by suppressing the satiety stimulus transmitted by CCK [6, 7].
Changes in ghrelin-related factors in gastroesophageal reflux disease in rats
Ghrelin was first discovered as an endogenous ligand for growth hormone secreting receptor (GHSR) (Kojima et al., 1999).
The effects of exercise on food intake and hunger: relationship with acylated ghrelin and leptin
This is required for ghrelin to bind to the growth hormone secretagogue receptor (GHSR) for its entry into the hypothalamus and pituitary gland, and to affect food-intake (26).
Effects of exercise on leptin and acylated ghrelin hormones in trained males
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