NKH kesin tanisi GLDC ve AMT genlerindeki mutasyonlarin gosterilmesi ya da enzim aktivitesinin yetersizligi ile konulur.
Comprehensive mutation analysis of GLDC, AMT and GCSH in nonketotic hyperglycinemia.
In addition, apigenin treatment has an influence on the genes involved in metabolism (SLC27A3, P4HB and GLDC
), DNA-dependent regulation of transcription (OVOL1 and OTP), cell signal transduction (ECT2, MAPK1IP1L, BMPR1A and AMFR), cell motility (AMFR), inflammatory response (CCR2) and other biological processes (HIP1R, ZDHHC2, NUP35 and SLC10A2).
(HAX606) FORREST WAYNE PATE, CEO of GOLDEN ENTERPRISES INC (GLDC
), describes the company's business and its background; prospects for the industry, with positive and negative trends; competitive threats; strategic opportunities for the firm including its marketing plans and acquisition potential; management strength and organization; and the financial prospects of the firm looking forward.
For example, more than 65% of the mutations in DMD  [dystrophin (muscular dystrophy, Duchenne and Becker types)] (which cause Duchenne muscular dystrophy) and approximately 20% of the mutations in GLDC [glycine dehydrogenase (decarboxylating)] (which cause nonketotic hyperglycinemia) are exonic deletions (1, 2).
Genomic deletion within GLDC is a major cause of non-ketotic hyperglycinaemia.