The clinical effects of GLOA can be divided into immediate, intermediate and long-term effects.
GLOA has been reported with virtual absence of major complications up to now.
However, this is challenged by the following first case presentation of a patient with atypical trigeminal neuralgia who developed a severe complication after a single GLOA procedure.
Under the clinical suspicion of triggered atypical trigeminal neuralgia by an external oral and maxillofacial surgeon, she received one transoral GLOA at the left GCS (ganglion cervicale superius) in a private oral and maxillofacial practice without using an analgetic specific medication (without a documented reason) before.
Beginning in 1980, ganglionic local opioid analgesia (GLOA) started to gain importance in Europe .
Herein, we provide the first report on a severely complicated course after a single GLOA at the left GCS with a hospital stay of four weeks, six surgical procedures, and a two-month stay in a rehabilitation clinic required for recovery.
Due to the aforementioned alternative treatment options, the course of our patient challenges the role of GLOA as a diagnostic and therapeutic tool in analgetic medicine especially for atypical TN (especially when no conservative analgetic treatment pathway was performed before any invasive method at all).
Kress, "Ganglionic local opioid analgesia (GLOA)," Der Schmerz, vol.
Maier, Ganglionare Lokale Opioidanalgesie (GLOA), Gerorg Thieme, Leipzig, Germany, 1996.