GPATS - What does GPATS stand for? The Free Dictionary
References in periodicals archive
Kim et al., "Expression and regulation of GPAT isoforms in cultured human keratinocytes and rodent epidermis," Journal ofLipid Research, vol.
AGPAT: 1- acyl-sn-glycerol-3-phosphate acyltransferase; DG: diacylglycerol; DGAT: diacylglycerol o-acyltransferases; G3P: glycerol-3-phosphate; GPAT: glycerol- 3phosphate acyltransferase; LPA: lysophosphatidic acid; PA: phosphatidic acid; PPAR[gamma]: peroxisome proliferator-activated receptor gamma; TG: triacylglycerol.
Conservation of catalytic residues suggested that LpxL is related to the glycerol-3-phosphate acyltransferase (GPAT
) family .
ACC: acetyl-CoA carboxylase; ACL: ATP-citrate lyase; AGPAT: 1-acylglycerol-3-phosphate acyltransferase; aP2: fatty acid binding protein; DGAT: diacylglycerol acyltransferase; ME: malic enzyme; FAS: fatty acid synthase; GPAT
: glycerol-3-phosphate acyltransferase; GPDH: glycerol phosphate dehydrogenase; LPL: lipoprotein lipase; MDH: malate dehydrogenase; OAA: oxaloacetate; PC: piruvate carboxylase; PDH; piruvate dehydrogenase; PEPCK: phosphoenolpyruvate carboxykinase; VLDL: very low-density lipoprotein.
Once formed, FA-CoA is used for the first acylation of glycerol-3-phosphate via glycerol-3-phosphate acyltransferase (GPAT
) enzymes, which produces 1-acylglycerol-3-phosphate (MAG-P) (Figure 2).