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GPVIGlobal Prospecting Ventures, Inc.
GPVIGenitoanal Papilloma Virus Infection
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Its biologic drug candidate is based on academic research on a platelet glycoprotein called GPVI, a platelet receptor of collagen and polymerized fibrin.
4FcRg is a dimer that forms a high-affinity complex with two molecules of GPVI on the surface of the platelet.
Rat monoclonal antibodies (mAbs) against human GPVI were developed and generated as described (15).
Plasma concentrations of sGPVI were determined by use of a bead-based sandwich immunoassay and mAb 8E9 reactive with human GPVI as capture antibody.
To test whether sGPVI is influenced by confounders, comparison of the decadic logarithm of GPVI between ACS and SAP was adjusted by possible confounders such as age, sex, cardiovascular risk factors, and medical treatment.
1] primarily supports platelet attachment to collagen, whereas GPVI and to a lesser extent [[alpha].
1], which is expressed on a variety of cells including platelets, and an immunoglobulin superfamily collagen receptor GPVI.
Glycoprotein VI is a major platelet glycoprotein (60-65 kd) that has been considered a putative receptor for collagen since the identification of a patient with a mild bleeding disorder whose platelets lacked GPVI and exhibited defective collagen-induced responses.
In compliance with the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995, GPVI notes that statements contained in this announcement that are not historical facts may be forward-looking statements that are subject to a variety of risks and uncertainties and there can be no assurance that other factors will not affect the accuracy of such forward-looking statements.