GPX1

AcronymDefinition
GPX1Glutathione Peroxidase 1
References in periodicals archive ?
Genetic polymorphisms (Pro197Leu of Gpx1, +35A/C of SOD1, -262C/T of CAT), the level of antioxidant proteins (GPx1, SOD1, CAT) and the risk of distal symmetric polyneuropathy in Polish patients with type 2 diabetes mellitus.
Polymorphic variants of MnSOD Val16Ala, CAT-262 C < T and GPx1 Pro198Leu genotypes and the risk of laryngeal cancer in a smoking population.
Tan et al., "hucMSC exosome-derived GPX1 is required for the recovery of hepatic oxidant injury," Molecular Therapy, vol.
Voidazan et al., "CAT, GPX1, MnSOD, GSTM1, GSTT1, and GSTP1 genetic polymorphisms in chronic myeloid leukemia: a case-control study," Oxidative Medicine and Cellular Longevity, vol.
Based on "omics" data which has been experimentally validated, molecules in circulating monocytes that are relevant to BMD may be categorized into processes such as apoptosis/survival (PLK3 and HSPB1), migration/chemotaxis (CXCL3, GSN, and HSPB1), adhesion (RSU1, HSPB1), transendothelial migration (ANXA2, HSPB1), differentiation into osteoclasts (STAT1, GBP1, ANXA2, and GSN), and other miscellaneous processes such as histamine biosynthesis (HDC), glucocorticoid sensitivity (GCR), regulation of oxidative stress (SOD2, GPX1), and protein folding (P4HB) and multifunctional molecules, miR-133a and miR422a (complete list of molecules identified and validated in Table 1).
Previous study found that PGC-1[alpha] was an essential factor for expression of several important antioxidant enzymes, including GPx1, Cu/ZnSOD, and MnSOD, which are responsible for clearing reactive oxygen species (ROS) [33].
Drzewoski, "Genetic polymorphisms (Pro197Leu of Gpx1, +35A/C of SOD1, -262C/T of CAT), the level of antioxidant proteins (GPx1, SOD1, CAT) and the risk of distal symmetric polyneuropathy in Polish patients with type 2 diabetes mellitus," Advances in Medical Sciences, vol.
SOD2, Gpx1, and CAT antioxidant enzyme protein levels were assessed by western blot as follows.
PGC-1[alpha] is PPAR-[alpha] activated factor, and it can reduce oxygen free radicals induced by NADPH oxidase and increase mitochondrial DNA and raise antioxidant enzymes such as MnSOD and glutathione peroxidase enzyme (GPx1).
Target genes were amplified and quantified by SYBR[R] green incorporation (EurobioGreen[R] Mix qPCR 2x Lo-Rox) with the following primers: 18S rRNA, forward: 5' AGA AAC GGC TAC CAC ATC CAA 3', reverse: 5' CAA TTA CAG GGC CTC GAA AGA 3'; sod1, forward: 5'ATT AAC TGA AGG CGA GCA TGG 3', reverse: 5' TCC AAC ATG CCT CTC TTC ATC 3'; sod2, forward: 5' TGG CTT GGC TTC AAT AAG GAG 37, reverse: 5' AAG ATA GTA AGC GTG CTC CCA 37; cat, forward: 5' CAT GAA TGG CTA TGG CTC ACA 3', reverse: 5' AAG TCT TCC TGC CTC TTC AAC 3'; gpx1, forward: 5' TGC AAT CAG TTC GGA CAT CAG 3', reverse: 5' TTC ACC TCG CAC TTC TCA AAC 37.
Resveratrol reduces endothelial oxidative stress by modulating the gene expression of superoxide dismutase 1 (SOD1), glutathione peroxidase 1 (GPX1) and NADPH oxidase subunit (NOX4).
Objective: To investigate the role of glutathione peroxidase 1 (GPX1) C/T polymorphism (rs1800668) in modulating the chances of Rheumatoid arthritis (RA) in Pakistani population.