GRNCMGraduate of the Royal Northern College of Music
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In contrast, ventricular tachycardia was induced in only 6 percent (1/15) of animals that received GRNCM I, suggesting a protective effect against arrhythmias in this acute model.
The results showed statistically significant improvements in left ventricular diastolic diameter (LVDD), left ventricular systolic diameter (LVSD) and fractional shortening (FS) in animals that received GRNCM 1 compared to controls.
Geron is currently conducting studies of GRNCM 1 in a swine model of myocardial infarction to further assess preclinical safety and efficacy of the product in an animal model with a cardiovascular system of similar size and structure to humans.