Abbreviations SPMs: Specialized proresolving lipid mediators DHA: Docosahexaenoic acid PMNs: Polymorphonuclear leukocytes Ri: Resolution interval EPA: Eicosapntemacnioc acid MCTR: Maresin conjugate in tissue regeneration sEH: Soluble epoxide hydrolase 12-LOX: 12-Lipoxygenase LTC4S: Leukotriene C4 synthase GSTM4
: Glutathione S-transferase MU 4 GGT: Gamma-glutamyltransferase DPEP: Dipeptidase NF-[kappa]B : Nuclear factor kappa B PDGF: Platelet-derived growth factor TGF-[beta]1: Transforming growth factor [beta]1 TRPV1: Transient receptor potential V1.
McMahon et al., "Loss of the Nrf2 transcription factor causes a marked reduction in constitutive and inducible expression of the glutathione S-transferase Gsta1, Gsta2, Gstm1, Gstm2, Gstm3 and Gstm4
genes in the livers of male and female mice," The Biochemical Journal, vol.
Finally, another haplotype in GSTM4
, occurring in 16-22 percent of the population, showed significantly decreased rates of growth for FEV1, FVC and MMEF.