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GISSGoddard Institute for Space Studies
GISSGeographic Information System Specialist
GISSGone in Sixty Seconds (movie)
GISSGerencia de Informática de la Seguridad Social (Social Security Department for Information Technology Management; Spain)
GISSGlobal Interconnect Sizing and Spacing
GISSGeneral Impression Shape and Size
GISSGordonstoun International Summer School (Scotland)
GISSGuidance Interface Subsystem
GISSGosh, I’m So Surprised! (Sci-Fi fandom)
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