Gary Goodyear, the federal Minister of State for Science and Technology, got to experience these specialized properties for himself when he was handed a syringe loaded with HAMC during a visit to Shoichet's lab this past June.
Shoichet's research at the U ofT has led to 30-plus patents (some covering HAMC formulations), more than a 110 peer-reviewed journal articles, at least 240 invited lectures and the training of 13 post-doctoral fellows and 46 graduate students.
CYP Substrate ([mu]M) Fluorescent Incubation Enzyme metabolite time (min) (pmol) 1A2 7-Ethoxyresorufin Resorufin 20 0.5 (1) 2A6 Coumarin(10) 7-Hydroxycoumarin 10 0.3 2B6 EFC (2.5) HFC 30 0.75 2C8 DBF (0.5) Fluorescein 30 1.5 2C9 MFC (75) HFC 45 1.5 2C19 DBF (0.5) Fluorescein 30 1.5 2D6 MAMC (20) HAMC
60 2.0 3A4 MFC (50) HFC 30 1.0 CYP Excitation/emission (nm) 1A2 570/615 2A6 355/460 2B6 405/535 2C8 485/535 2C9 405/535 2C19 485/535 2D6 405/460 3A4 405/535 Abbreviations: EFC.
The HAMC said in a press statement that the strike came against the Israeli police, which attacked the Palestinians during a march of Israeli right-wing activists in the city on Wednesday.
Abed Anabtawi, HAMC secretary, said all businesses and schools in the city were almost shut down.
The HAMC demanded that Israeli President Shimon Peres and Prime Minister Benjamin Netanyahu set up an investigation committee to look into the violent events.
They are afraid of Israeli diplomatic pressure, so they said they would rather it not get out," HAMC
secretary Abed Anabtawi said.
Steve Nicholas (aka Echo), HAMC
Wales, Newtown, Powys
The Higher Arab Monitoring Committee (HAMC) also declared a general strike in all Arab towns to mark the anniversary.
HAMC said that all Arab cities and towns, including Umm el-Fahm, Sakhnin, Arrabeh, Taybeh, as well as Arab neighborhoods in mixed cities such as Haifa and Jaffa, closed their businesses, local authorities said.