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Three haplotypes were identified in China: Hap1 (dark red), Hap2 (orange), and Hap3 (dark yellow).
Zhang, "Functional analysis of heme regulatory elements of the transcriptional activator Hap1," Biochemical and Biophysical Research Communications, vol.
The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites.
They have identified the 3-D structure of a crucial protein molecule, HAP1, which could provide the key to killing tumours.
The haplotype networking has shown that Hap1 contributed 48.051% and appeared in six populations whereas, Hap6, Hap11, Hap 16 and Hap17 were also shared by some populations, rest of the haplotypes were unique.
Hap1 and Hap3 were the shared haplotypes in generations 0 and 5, with Hap5 shared haplotype in generations 10, 15, 16, and 17.
Among the 6 pure populations in the SD clade (i.e., populations that were 100% Hap1) (Zhang et al.
Robson et al., "Identification of critical active-site residues in the multifunctional human DNA repair enzyme HAP1," Nature Structural Biology, vol.
Hersch, "The cellular and subcellular localization of huntingtin-associated protein 1 (HAP1): comparison with huntingtin in rat and human," Journal of Neuroscience, vol.
We detected haplotypes structure and found the common haplotype (hap1) had a relatively high frequency in two breeds, for the haplotype was present in the population for a long time.
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- Haole rot
- Hap Arnold
- Hap ki do
- Hapag Lloyd Express
- Hapag Lloyd Flug
- Hapag Lloyd Kreuzfahrten
- Hapag-Lloyd Container Line
- Hapalochlaena fasciata
- Hapalochlaena lunulata
- Hapalochlaena maculosa
- Hapax legomen
- hapax legomena
- hapax legomenon