HAQ-DIHealth Assessment Questionnaire Disability Index
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Efficacy signals were observed for each of ACR 20/50/70, ACR-N, HAQ-DI, SF-36 and DAS-28 disease activity score.
There were also greater reductions in the HAQ-DI score at month 3 and higher percentages of patients achieving remission at month 6 in the active-treatment groups than in the placebo group.
The HAQ-DI scale has a 0-3 range, with 0 indicating no difficulty in the activities of daily living, and 3 indicating complete disability.
The HAQ-DI is derived from a questionnaire comprising eight subscales: dressing, arising, eating, walking, reaching, gripping, hygiene, and carrying out common activities.
The positive correlation between HAQ-DI and pain intensity mirrored the reality of disease experience, and the relationship between HAQ-DI and ACR classification demonstrated similar patient/ physician perceptions on functioning.
Multivariate analysis was applied to determine the correlations between sexual disability and loss of sexual desire and satisfaction and age, duration of RA, scores of disease activity, HAQ-DI, NRS, depression and anxiety.
1%, respectively, had a 20% or greater improvement in HAQ-DI, compared with 47.
Means and standard deviations of fatigue severity scale, SF-36 subscales, and HAQ-DI score are presented in Table 4.
In the IMPACT-2 trial, the median improvement in the HAQ-DI score was 43% from those on infliximab at week 14, vs.