HAS2Hyaluronic Acid Synthase 2
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Tested at 2%, YE significantly increases HAS2 expression by 651% compared to non-treated normal human fibroblasts.
By increasing the expression of the HAS2 synthesis, YE boosts the endogenous production of hyaluronic acid.
Figure 1: Effect of YE tested at 2% on the endogenous production of hyaluronic acid by normal human fibroblasts Control YE TGF-[beta] (2%) (10 ng/ml) Study of the synthesis of 1280 4309 * 2343 * hyaluronic acid Study of the expression 100 751 * 318 * of HAS2 *: significant results according to Student's t test (P < 0.
These unique amino acid changes may be responsible for the high processivity of the naked mole rat HAS2 protein- in charge of HA synthesis.