HAUSP


Also found in: Medical.
AcronymDefinition
HAUSPHerpesvirus-Associated Ubiquitin-Specific Protease
References in periodicals archive ?
Jochemsen, "ATM-mediated phosphorylations inhibit Mdmx/Mdm2 stabilization by HAUSP in favor of p53 activation," Cell Cycle, vol.
HAUSP, or herpesvirus-associated ubiquitin specific protease, is an enzyme that cleaves the normally occurring protein ubiquitin from substrates like p53.
"Given the mounting evidence that HAUSP serves as a pivotal component regulating p53 protein levels, the inhibition of HAUSP should have the benefit to fully activate p53," said Hye-Ra Lee, Ph.D., the study's first author and a research fellow in the Department of Molecular Microbiology and Immunology at the Keck School of Medicine of USC.