A case was defined as 1) diagnosis of EKC, adenoviral conjunctivitis, or viral conjunctivitis by an ophthalmologist or optometrist; or 2) laboratory confirmation of HAdV
from a specimen collected by conjunctival swab in a person seen at the optometry clinic during June 5-July 3, 2017.
Prior to this study, limited data were available regarding the epidemiology of HAdV
in hospitalized children with viral diarrhea in Shanghai, and most studies have focused on RVA and HuCV infections [7-9].
7e-h), the CONV and HADV
terms increased to an order of magnitude larger than VADV and TILT The HADV
term still exhibits a positive (negative) maximum at the southwest (northeast) flank of the mesocyclone center.
All samples were tested with Infiniti RVP plus assay on Infiniti Plus analyzer which identifies the following respiratory viruses: Influenza A virus (FluA), Influenza B virus (FluB), Influenza A-Swine H1N1 virus, hPIV (1,2,3, and 4), hRV (A and B), EV (A , B , C, and D), hCoV (HKU1 , OC43 , NL63, and 229E), hMPV (A and B), hRSV (A and B), and hAdv
(A, B, C, and D) with 90% sensitivity and 100 specificity according to manufacturer (AutoGenomics, USA).
Remarkably, many of the HAdV
E3 proteins preferentially interacted with host receptors that exert known or predicted inhibitory functions during the immune response (as defined by the presence of intracellular immunoreceptor tyrosine-based inhibitory motif, ITIM), including LILRB1 [81, 82], LAIR1 , and MPZL1 , suggesting previously unrecognized strategies of immunosuppression that may be utilized by other human pathogens .
Therefore, we performed molecular genotyping of HAdV
strains in stool specimens collected from patients with acute gastroenteritis in Korea from 2014 to 2016, with the aim of investigating the incidence of AdV gastroenteritis, the distribution of AdV genotypes, the types other than types 40 and 41 that might be associated with gastroenteritis, and the relationship between AdV genotypes and clinical symptoms.
Previous studies have demonstrated an association between asthma and infections with various respiratory viruses, including HRSV, HRV, HMPV, HPIV, HAdV
, and FLUV.
Within the Lyra brand, Quidel also offers FDA-approved molecular diagnostic tests for 15 different infectious agents, including eleven molecular tests for respiratory disease (Strep A, Strep C+G, Influenza A, Influenza B, human metapneumovirus (hMPV), respiratory syncytial virus (RSV), adenovirus (HAdV
), and HPIV-1, -2, and -3) and four other PCR assays for other serious infectious disease pathogens (herpes simplex virus (HSV) types 1 and 2, varicella zoster virus (VZV) and C.
A research conducted in New Zealand  reported that Human Adenovirus (HAdV
) species C and F, and Norovirus GI and GII were frequently detected in municipal sewage and biosolid samples.
(20-22) Epidemiologic research examining the genetic variability of human adenovirus (HAdv
) strains, prospective surveillance for vaccine-targeted HAdv-4 and HAdv-7 strains, and early detection of vaccine breakthrough infections continued to be implemented by scientists at the Lovelace Respiratory Research Institute and NHRC.
The same database, which contains a nonredundant protein database for both human and HAdVs
proteins (http://www.uniprot.org/) and a few of HAdV
entries derived from NCBI, was applied for both PP and Mascot searches.