Meanwhile, serum markers such as CK, AST, ALT, LDH, HBDH, and anti-Jo-1 were also found to be strongly correlated with the presence of ILD in DM patients.
VAS: Visual analog scale; IL-18: Interleukin-18; CK: Creatine kinase; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; LDH: Lactate dehydrogenase; HBDH: Hydroxybutyrate dehydrogenas.
MITAX: Myositis Intention to Treat Activities Index; IL-18: Interleukin-18; CK: Creatine kinase; AST: Aspartate aminotransferase; ALT: Alanine aminotransferase; LDH: Lactate dehydrogenase; HBDH: Hydroxybutyrate dehydrogenase.
Blood levels of WBC, CRP, LDH, HBDH, and Ferritin were significantly higher in severe than in mild groups (Table 2).
The activity of HBDH is increased with PCP, correlating positively with LDH (P = 0.000, [R.sup.2] = 0.882, data not shown) and negatively with oxygenation index (P = 0.001, [R.sup.2] = 0.335), indicating that HBDH is likely to be reflection of the underlying lung inflammation.
In conclusion, our data suggest that detection of plasma IL-8 levels and IL-6/IL-10 ratio combined with LDH and HBDH can predict the severity of PCP risk of death in AIDS patients with PCP.
(a) LDH (95% CI 0.636-0.956, P = 0.006), HBDH (95% CI 0.7030.985, P = 0.001), and FeP (95% CI 0.657-0.993, P = 0.002) showing much higher AUC in severity AIDS PCP groups.
(a) LDH (95% CI 0.675-0.970, P = 0.010), HBDH (95% CI 0.797-0.989, P = 0.006), and FeP (95% CI 0.541-0.991, P = 0.034) showing much higher AUC in nonsurvivors AIDS PCP groups.
FHb and the HBDH values were higher than the reference values in humans [FHb, <0.3 g/L; HBDH, <140 U/L (14)] in the room temperature samples.
Both FHb and HBDH increased further 48 h after warming to room temperature (P < 0.001 compared with measurements immediately after heating for all temperatures).
The concentrations of FHb and HBDH were measured at room temperature, at 52[degrees]C, and in the dilutions 1:8, 1:32 and 1:64 [Table 5 of the online Data Supplement (available at http://www.clinchem.
FHb and HBDH. Twelve units of PRBCs [mean (SD) age, 32.5 (8.3) days; weight, 343.8 (29.2) g] were used.