Using Fisher test, comparing % Hb F in the form of Mean [+ or -] SD among HbSS and HbSA groups, we find that for HbSS participants it is 19.09 [+ or -] 6.4 which is significantly greater than that of HbAS groups 1.9 [+ or -] 2.5 (p=0.000).
HPLC diagnosis Sample count % HbA2 n (%) HBSS 13 (27.7) 2.7 [+ or -] 0.7 HBSA 18 (38.3) 3.64 [+ or -] 1.06 HbS/[beta]-thal 3 (6.4) 4.8 [+ or -] 1.3 (mild) HbS/[beta]-thal 2 (4.2) 4.4 [+ or -] 1.48 (moderate) Healthy 11 (23.4) 2.1 [+ or -] 0.5 HPLC diagnosis % HbF % HbS HBSS 1.9 [+ or -] 2.5 36.2 [+ or -] 4.2 HBSA 19.09 [+ or -] 6.4 77.80 [+ or -] 7.2 HbS/[beta]-thal 6.1 [+ or -] 3.4 70.6 [+ or -] 0.6 (mild) HbS/[beta]-thal 20.85 [+ or -] 8.3 65.85 [+ or -] 14 (moderate) Healthy 0.6 [+ or -] 0.7 0 HPLC diagnosis % HbA HBSS 59.06 [+ or -] 6.2 HBSA 0 HbS/[beta]-thal 18.4 [+ or -] 2.9 (mild) HbS/[beta]-thal 8.85 [+ or -] 4.3 (moderate) Healthy 97.4 [+ or -] 0.4 Values are represented as mean [+ or -] SD.
Peter Gilbert, long-serving HBSA member and its webmaster, said: "In my opinion and in my experience Canalside appears to be dying.
The HBSA boasts 47 active clubs with 136 teams and more than 1,100 players aged 14 to 90-plus.
In case with HbSS anisocytosis and poikilocytosis were more frequently seen compared to HbSA. Normoblast were few in numbers, but target cells were plenty.
But it was absent in case of HbSA. The mean values of all the six parameters of HbAA, HbEA, HbSA and HbSS were studied [Table-4].
In case of HbSA compared to HbSS, the MCV mean value was low, mean value of Hbgm% was high.
Few normoblasts were seen in HbSS, but seen occasionally in HbSA. Few sickle cells were seen in HbSS.
Andy Earnshaw, the business development manager from SMileS, who sponsor the League, said: "We have been pleased to sponsor the HBSA
during its 75th anniversary year and, in particular, we are looking forward to meeting Nigel Bond at the annual presentation evening."