16 The present study, the first of its kind, was planned to investigate the prevalence and transmission risks of
HBV and HCV infections among IDPs.
Different serologic markers are used to identify different phases of
HBV infection and to determine whether a patient has acute or chronic
HBV infection, is immune to
HBV as a result of prior infection or vaccination, or is susceptible to infection.
According to World Health Organization (WHO) approximately more than 2 billion people are infected with
HBV globally, including about 400 million people with chronic stage of infection while every year, approximately 0.
The aim of this study was to determine the
HBV genotypes and subgenotypes circulating in the Ribeirao Preto region and to compare the genetic sequences found with
HBV sequences previously described in different parts of the world by phylogenetic analysis.
Results: The BMD values were significantly lower in
HBV patients in all scan of specific regions compared with the controls (P < 0.
Noting the direct correlation between increasing levels of serum
HBV DNA and risk of hepatocellular carcinoma (HCC) over time, he indicated that reducing
HBV DNA replication already reduces risk of complications.
Worldwide,
HBV infection is the most common cause of hepatitis.
Assembly aims to improve on the current low cure rates for chronic
HBV by targeting the
HBV core protein, an essential viral protein involved in multiple critical functions throughout the
HBV lifecycle.
Occult hepatitis B virus infection/carriage (OBI) is characterized by the presence of very low levels of
HBV DNA in plasma and/or in liver, with undetectable HBsAg using the most sensitive commercial assays, with or without antibodies to antiHBc or hepatitis B surface antigen (anti-HBs) outside the pre-seroconversion window period.
In accordance with prevalence of
HBV in general population3, world is divided in to three zones; high prevalence zone (>8%), intermediate (2-8%) and low (less than 2%) prevalence zone.
The focus of this study is on understanding the role of host factors in
HBV transmission in coastal Odisha, especially with regard to OBI.
Chronic
HBV infection is therefore frequent among people living with HIV/AIDS in sub-Saharan countries, with reported
HBV surface antigen (HBsAg) seroprevalence rates of 7-15% in West Africa [3,4] and East Africa.
