HCFDHarrods Creek Fire Department (Jefferson County, KY)
HCFDHigh-Calorie/High-Fat Diet
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After a one week adaptation, rats were randomly divided into three groups (n=8 rats each) as follows: Control group (Control): non-diabetic, non-treated rats that were injected intraperitoneally (i.p.) once with citrate buffer (0.1 M, pH 4.5) and fed with standard laboratory chow for 12 weeks; Diabetic type 2 group ( T2DM): rats were fed a high carbohydrate and fat diet (HCFD) (Collino et al., 2010) for two weeks and then DM was induced in rats by a single i.p.
Blood levels of hs-CRP (A) and ALP (B) were measured in 4 groups of rats; Control, Control + exercise (Control + EX), HCFD, and HCFD + exercise (HCFD+EX) groups after 15 weeks.