HCRTHyperthermo-Chemo Radio-Therapy
HCRTHigh Country Rail Trail (Australia)
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[sup][11],[12],[13],[14],[15],[16],[17],[18] Nevertheless, the precise roles of the signaling pathways of HCRT in narcolepsy remain unclear.
[sup][19],[20] Xingshentongqiao decoction (XSTQ), a significantly effective traditional Chinese medicine preparation for narcolepsy, is intended to correct the basic pathogenesis of the imbalance of yin and yang for narcolepsy, and this preparation uses herbs that have been proven to have obvious effects targeting the signaling pathways of HCRT. [sup][21] This study aimed to explore the molecular mechanism of XSTQ in targeting the HCRT signaling pathway for narcolepsy.
Deficiency of the HCRT system has been confirmed as an underlying cause of most cases of narcolepsy.
Xingshentongqiao decoction upregulates OX1R and OX2R expression in SH-SY5Y cells in vitro , which could play a critical role in the activation of HCRT signaling pathways in narcolepsy.
Orexins, also known as HCRTs, are neuropeptides produced in neurons of the lateral and dorsomedial hypothalamus and perifornical area, which project widely throughout the brain.
A Host Country Research Team (HCRT) was assembled, including a research coordinator, two regional field coordinators, and ten field researchers.
For example, in October 11993 the HCRT Research Coordinator participated in NEU seminars for teachers, parents, and pupils in the two regions to discuss the findings from pre-test data and to review vignettes (transcribed from videos recordings) of classroom interaction in NEU and EU schools.
Additionally, on 30 May and 2 June 1995, the HCRT coordinator conducted workshops for teachers working in NEU schools in Region II and Region IV, respectively.
By April 1993, when formal "cooperative agreements" were signed, it had been decided to create a Host Country Research Team (HCRT) composed of eight members, four members each from the following two education ministry units, which from October 1992 were located organizationally in two different ministries: (1) the Institute P[acute{e}]dagogique Nationale (National Pedagogical Institute or IPN), the technical research branch of the Ministry of Basic Education, and (2) the Institute Sup[acute{e}]riere de Formation et de Recherche Appliquee (Higher Institute of Training and Applied Research or ISFRA), a research unit of the Ministry of Secondary and Higher Education.
Following the Colloque, the HCRT (with the guidance of U.S.
Moreover, subsequent delineation of the research design was undertaken primarily by a U.S.based researcher and a Colombian, who was working for a U.S.-based consulting firm was overseeing the implementation of the NEU program, in addition to the HCRT Coordinator.