HDAC


Also found in: Medical.
AcronymDefinition
HDACHistone Deacetylase (biochemistry)
HDACHuntington's Disease Advocacy Center (Stanford, CA)
HDACHouse Democracy Assistance Commission (US House of Representatives)
HDACHydrogen/Deuterium Absorption Cell
HDACHuman Developmental Anatomy Center (National Museum of Health & Medicine; Washington, DC)
HDACHelen Day Art Center (Stowe, VT)
HDACHeavy Duty Air Cylinder
References in periodicals archive ?
Rodin Therapeutics is discovering and developing first-in-class therapeutics for synaptopathies by applying novel chemical strategies to target specific HDAC complexes and upregulate key neuronal genes.
Specifically, Hdac will use the DevOps approach to enable fast and easy development, establishment, test and distribution of Hdac-based blockchain infrastructure.
A number of HDAC inhibitors have been reported to date that cause tumor cell growth arrest at doses that are apparently nontoxic and appear to be very selective.
When conducting this study, TSA, a potent and reversible class I and II HDAC inhibitor, was applied to poorly differentiated PANC-1 cells.
Apart from its antiepileptic property, VPA is a well-recognized histone deacetylase (HDAC) inhibitor.
Chidamide is a selective HDAC inhibitor with unique epigenetic mechanisms against tumor cell growth, immune escape and drug resistance.
Targeting HDAC. The nucleosome is composed of four core histones (H3, H4, H2A, and H2B) wrapped around with 147 base pairs of DNA [18].
HDAC inhibitors are emerging anticancer agents [12-14] and promising for the treatment of cerebral ischemia, spinal muscular atrophy, and neurodegenerative conditions such as Alzheimer's disease, Parkinson's disease, and Huntington's disease [6,15].
The antibacterial activities of porcine 3D4/31 cells treated with selected HDAC inhibitors were assessed as described [17, 37, 38].
"An open beta service, trial test of the HDAC trading is set to begin Jan.