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Related to HDCV: rabies immunoglobulin
HDCVHuman Diploid Cell Vaccine
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References in periodicals archive ?
To overcome the high cost of HDCV and to make rabies vaccine more affordable to common people, other cell culture rabies vaccines were developed that are less expensive to produce and cause fewer adverse reactions.
In the fiscal year 1980-81, the ministry began distributing the newly licensed HDCV to replace earlier Semple and duck embryo vaccines.
The estimated cost of providing PEP during this study was A$137,368, which included A$30,930 for medical services funded through the Commonwealth Medicare system (calculated on the cost of six visits to a medical practitioner for each person requiring a 5-dose course of PEP and three visits for each person requiring 2 doses of PEP); A$8,200 for public health officers who interviewed potentially exposed persons; A$10,600 for laboratory testing of the bats; and A$87,638 for HDCV and HRIG.
Each of these received two further intramuscular doses of 1.0 ml of HDCV, according to the Australian recommendations for postexposure treatment of vaccinated persons.
Preexposure vaccination with HDCV or rabies vaccine adsorbed should be considered for persons living in or visiting (for [is greater than] 30 days) areas where rabies is endemic and appropriate PEP may not be readily obtained.
Because rabies had been considered in the differential diagnosis, on April 24, 1 dose (800 IU) of human rabies immune globulin (HRIG) and 1 mL of human diploid cell rabies vaccine (HDCV) were administered intramuscularly, and he was transferred to a pediatric hospital.
HDCV is prepared from the Pitman-Moore strain of rabies virus grown in MRC-5 human diploid cell culture and concentrated by ultrafiltration (23).